Endocrine Abstracts

Graves’ disease (GD) and thyroid-associated ophthalmopathy (TAO) are often observed together. In purpose to elucidate the pathogenetic relationships between these two autoimmune disorders we investigated profile of different autoantibodies in patients with GD without TAO (n=38, group 1), GD with TAO (n=40, group 2), and in healthy people (n=124, control group). Autoantibodies to thyroid gland, eye muscle cell membranes (Ab-EMCM) and skin fibroblasts w...

Androgens play an important part in follicular development, sexual behavior, maintenance of skeletal homeostasis, normal affect and cognitive function. The negative influence of androgen deficiency is widely discussed in postmenopausal women. However, there is a cohort of young women with gonadal steroid deficit caused by the disorders of central regulation. It is well known that these patients are in lack of estrogens however their androgen status is not detailed.<p class...